The fact that immunodeficient mice have become standard tools in hematology and immunology research is thanks in part to initiatives started in the early 1970s to reunite researchers in the field ...
To develop the model, Keck and his team used three different immunodeficient mouse strains engrafted with the peripheral blood mononuclear cells (PBMC) from 10 healthy human donors. These ...
HMA mice are germ-free strains in which human gut microbiota are established through fecal transplant. Researchers can examine disease phenotypes of germ-free mice colonized with the fecal microbiota ...
NOD scid gamma (NSGTM), a highly immunodeficient mouse only available from The Jackson Laboratory, provides the unmatched ability to model normal and malignant tissues and cells notoriously difficult ...
The CAST/EiJ mouse, part of a research panel including eight genetically diverse mouse strains, stands out for its severe response to SARS-CoV-2 infection, including beta, omicron, and delta variants.
But Jung and colleagues noticed that some immunodeficient mouse models couldn't be colonized with C. albicans even after ...