Transgenic and knockout mice have been used to create disease models and understand gene function. However, such mice are complex to create, breeding colonies must be established, and some models ...

The team’s novel technique, detailed in a paper published in Advanced Functional Materials ( "In Vivo Screening of Barcoded ...

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.

Researchers find blocking the KCNB2 gene can slow tumor growth, paving the way for next-gen treatments for childhood brain cancer.

Crispant analysis in zebrafish serves as a powerful tool for the rapid functional screening of genes implicated in bone fragility disorders, like osteogenesis imperfecta and osteoporosis.

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation ...