Microorganism- and host-derived 'danger' signals stimulate formation of a multiprotein complex, termed the inflammasome, which leads to processing and activation of caspase 1. Active caspase 1 ...

Credit: Nevit Dilmen / Wikimedia Commons" /> Credit: Nevit Dilmen / Wikimedia Commons The paper: S. Mariathasan et al., "Cryopyrin activates the inflammasome in response to toxins and ATP," Nature, ...