Since then, the mucosal immune system has received a great deal of attention and is described as an integrated network of tissues, cells and effector ... pathogens in the gastrointestinal system ...

When these mechanisms fail, pathogenic effector ... in the gastrointestinal tract Jiri Mestecky, MD, PhD Molecular-cellular interactions involved in the differentiation of B lymphocytes and epithelial ...

Secondly, the key element of the intestinal barrier affecting permeability are described. This barrier represents a huge mucosal surface, where billions of bacteria face the largest immune system ...

With every bite of food we take, our intestinal immune system must make a big decision ... head of the Laboratory of Mucosal Immunology. After optimizing LIPSTIC for the task, Canesso and ...

More information: Samantha Y. Tse-Kang et al, Intestinal immunity in C. elegans is activated by pathogen effector-triggered aggregation of the guard protein TIR-1 on lysosome-related organelles ...

These tissues are closely associated with the external environment and the mucosal immune system must provide protective ... microbiome in a murine model of intestinal inflammation.

Colorectal cancer stands as one of the leading malignancies in the digestive system, ranking third ... growth by suppressing CD8+ T cell effector functions, Immunity (2024). DOI: 10.1016/j.immuni.

These interactions are crucial for triggering various effector functions of the immune system ... encountered at mucosal surfaces, such as those of the respiratory and gastrointestinal tracts.

Most regions of the world chose OPV to eradicate polio, because it could induce an intestinal mucosal immunity and prevent spread of polio virus, induce longer immunity, was cheaper and easier to ...