Intrathecal baclofen (ITB) therapy has evolved into a standard treatment for severe spasticity. After this therapy had been provided for 10 years, a retrospective chart review on 50 patients ...

Intrathecal baclofen therapy (ITB) is a specialized treatment used to manage severe spasticity, particularly in patients with conditions such as cerebral palsy and spinal cord injuries.

Practitioners from around the country who have extensive experience in intrathecal baclofen (ITB) therapy gathered in early 2004 to develop best-practice guidelines for ITB therapy. Discussion ...

The patient was then trialed on intrathecal baclofen therapy via lumbar puncture, which led to immediate symptomatic relief. Given the good response, the patient underwent surgical implantation of an ...

OBJECTIVE--To investigate whether the dose of intrathecal baclofen necessary for a sufficient reduction of muscle tone and spasms changes during treatment of severe spasticity. METHODS--A group of 27 ...

A literature review revealed a case report demonstrating the effective and well tolerated use of subcutaneous baclofen in a patient who could no longer take his medications via PEG. A decision was ...

The intrathecal version injects the gene therapy directly into the spinal cord, thereby allowing for a smaller dose needed to have enough therapeutic payload reaching the motor neurons ...

1 There is a limited body of scientific literature on severe baclofen intoxication, resulting in a burst-suppression pattern in the EEG and a clinical manifestation with profound coma and the absence ...

Undiagnosed hypogonadism in intrathecal opioid therapy patients may lead to low bone mineral density levels ... with combinations of morphine with bupivacaine (12.5%), morphine with bupivacaine and ...