Novartis (NYSE:NVS) said a Phase 3 study of an intrathecal formulation of its gene therapy Zolgensma ... The product, which ...

infection of an implanted intrathecal pump can lead to meningitis. Such problems are becoming more common (Teddy, Jamous, Gardner, Wang, & Silver, 1992). Baclofen is a classic medication for ...

The two major invasive interventions for managing spasticity are administration of intravenous and intrathecal medication (discussed above) and chemodenervation. Before using invasive treatment ...

Novartis (NYSE:NVS) said a Phase 3 study of an intrathecal formulation of its ... The product, which is one of the most expensive drugs in the world, is used to treat SMA in children younger ...

Novartis intrathecal onasemnogene abeparvovec phase III STEER study meets primary endpoint in children and young adults with SMA: Basel Tuesday, December 31, 2024, 11:00 Hrs [IST] ...

Intrathecal administration ... Consider discontinuing drugs that may lower the seizure threshold (eg, phenothiazine derivatives, tricyclics, MAOIs, CNS stimulants, analeptics, antipsychotics ...

Intrathecal administration ... Consider discontinuing drugs that may lower the seizure threshold (eg, phenothiazine derivatives, tricyclics, MAOIs, CNS stimulants, analeptics, antipsychotics ...

Novartis said it plans to share the Steer results with regulators, including the FDA, to seek approvals for OAV-101 IT. Grant said a submission is expected in the first half of 2025. Novartis had ...

This pivotal study assessed the efficacy and safety of investigational intrathecal onasemnogene abeparvovec (OAV101 IT ... a procedure designed to mimic the administration of an investigational drug, ...