The two major invasive interventions for managing spasticity are administration of intravenous and intrathecal medication (discussed above) and chemodenervation. Before using invasive treatment ...

infection of an implanted intrathecal pump can lead to meningitis. Such problems are becoming more common (Teddy, Jamous, Gardner, Wang, & Silver, 1992). Baclofen is a classic medication for ...

Novartis (NYSE:NVS) said a Phase 3 study of an intrathecal formulation of its ... The product, which is one of the most expensive drugs in the world, is used to treat SMA in children younger ...

Intrathecal administration ... Consider discontinuing drugs that may lower the seizure threshold (eg, phenothiazine derivatives, tricyclics, MAOIs, CNS stimulants, analeptics, antipsychotics ...

Novartis said it plans to share the Steer results with regulators, including the FDA, to seek approvals for OAV-101 IT. Grant said a submission is expected in the first half of 2025. Novartis had ...

intrathecal use). Ensure adequate hydration ... Consider discontinuing drugs that may lower the seizure threshold (eg, phenothiazine derivatives, tricyclics, MAOIs, CNS stimulants, analeptics ...