The realization that most human genes generate multiple mRNAs encoding divergent protein isoforms via alternative splicing and polyadenylation has revealed extensive regulation that remains to be ...

These loci were just as often associated with differences in genetic expression caused by NMD as they were with differences in production of multiple protein isoforms. Li believes cells sometimes ...

In this way, the researchers were able to analyse how each protein isoform affects the cell. According to Dr Sarah Buchholz, ...