Itaconate is a metabolite derived from the Krebs cycle, primarily produced in activated macrophages. Recent research has highlighted its significant role in modulating inflammation and immune ...

Researchers identify SLC13A3 as a key player in tumor cell survival and immune therapy resistance, highlighting its potential ...

In a new study, published in the journal Cell Reports, the team identified an inflammation-reducing molecule—called itaconate (ITA)—that could be the foundation of a new approach to treat such ...