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生物通
25 天
Piezo1 蛋白:椎间盘退变机制新发现与潜在治疗靶点
为探究 Piezo1 在椎间盘退变(IVDD)中的作用,研究人员经多项实验发现其通过 Ca 2+ /F-actin/Yap 轴促进退变,为 IVDD 治疗提供新策略。 椎间盘退变(Intervertebral disc degeneration,IVDD)是引发下腰痛及其他椎间盘疾病的 “罪魁祸首”。随着年龄增长,IVDD 进程加速 ...
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