Jamie-Lynn Sigler is reflecting on the scariest time in her life when her 11-year-old son Beau was hospitalized with a life-threatening autoimmune condition last summer. “Those were the hardest ...

He was the first person on the set of the HBO drama that Sigler told about her diagnosis. Jamie-Lynn Sigler discovered a ...

“I just didn’t know what that would mean for me to say it out loud and have everybody know,” Jamie-Lynn Sigler says in PEOPLE’s exclusive clip of her and Christina Applegate’s new ...

Some seven months after her son Beau was hospitalized for 33 days with a rare autoimmune condition, Jamie-Lynn Sigler is now sharing some of the harrowing details of his fight for life.

In an exclusive clip from their new podcast, MeSsy, Sigler credits Applegate with being "honest and open and vulnerable in a way that took me 22 years to get to" Jamie-Lynn Sigler has been living ...

Last month she appeared on the cover of People with Christina Applegate—two actors mass audiences first embraced for their roles as sweet and strong-minded daughters in TV series of decades past.

Applegate revealed in an episode of the podcast "MeSsy," which she co-hosts with fellow actress Jamie-Lynn Sigler, that she's been in and out of urgent care constantly since being diagnosed with MS.