Hcy-induced MCP-1 and IL-8 production is mediated by activated signaling pathways such as PKC, CaM, MAPK, and NF-κB. Our results not only provide clues for the signal transduction pathways ...

Molecular pathways that influence cellular life-and-death decisions increasingly fall under the scientific spotlight. In 1996, researchers discovered that NF-kB is anti-apoptotic, which led to the ...

Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...