We present a one-step, visible light-induced synthesis of bicyclo[1.1.1]pentane-ketone, a bioisostere for benzoyl groups that ...

forming two additional ketone (carbonyl) groups. The loss of hydrogen indicates an oxidation reaction (increasing the oxygen to hydrogen ratio) and the molecule will also lose two electrons.

Specifically, the researchers found in HFpEF hearts, ketone use was impaired, as well was also an impaired glucose oxidation rate coupled with an increase in fatty acid oxidation. These two ...