Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

The study, published in Science Translational Medicine, highlights the role of type 5 collagen—a minor component of scar ...

Key takeawaysUCLA researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as ...

Apr. 9, 2025 — Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed ...

When the UCLA team gave Cilengitide to mice with low type 5 collagen, it slowed down the scarring and kidney damage.

Deficiency of the pancreatic progenitor cell differentiation and proliferation factor gene was identified as a risk factor for chronic kidney disease in preclinical studies, representing a potential ...

Researchers have long understood that PKD is associated with kidney cysts and fibrosis and a gradual decline in renal function – a measure of the kidney's ability to remove waste and fluid from ...