Statin therapy greatly reduces LDL-cholesterol levels and slows progression of coronary atherosclerosis. The small statin-induced increases observed in HDL-cholesterol levels have not, however ...

In comparison, high-density lipoprotein works to reduce cholesterol levels by absorbing it and carrying it back to the liver.

with smaller LDL particles widely considered to be more closely associated with atherosclerosis and coronary heart disease. Recent evidence suggests that it is the total number of circulating LDL ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

A study published by researchers from the Sant Pau Research Institute (IR Sant Pau) and the Stroke Unit of Sant Pau Hospital ...

Cholesterol is crucial for the body's functioning, but an imbalance with high LDL can lead to serious cardiovascular problems ...

[Grundy SM, et al. Circulation. 2018;2b] Because of the central role of LDL-C in the pathogenesis of atherosclerosis, LDL-C-lowering pharmacotherapy is the cornerstone of medical management of ASCVD.

Jiangsu Hansoh Pharmaceutical Group Co. Ltd. and Shanghai Hansoh Biomedical Co. Ltd. have divulged proprotein convertase subtilisin/kexin-type 9 (PCSK9) inhibitors acting as LDL-lowering agents ...