Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer ...

LPS, also known as endotoxin, is a molecule found in the outer membrane of many different types of bacteria. Through its interaction with TLR4, LPS induces a strong inflammatory reaction in humans.

Toll-like receptor (TLR) recognition of microbial compounds initiates signalling cascades that activate inflammatory and immune-response genes. A recent report in Nature shows that the nuclear ...