The crucial drugs can have unintended consequences. Innovative therapies could shield the microbiome from their effects.
AbbVie has announced that the US Food and Drug Administration (FDA) has approved its Pfizer-partnered Emblaveo ...
Beta-lactam antibiotics are the most widely used class of drugs for the treatment of bacterial infections. They include penicillin and its derivatives, such as methicillin and amoxicillin, as well as ...
AbbVie has claimed FDA approval for Emblaveo, a new antibiotic product to treat complicated intra-abdominal infections (cIAI) ...
The β-lactams inactivate the DD-transpeptidases by acylating their essential active-site serines. The sensitivity of the target to the antibiotic is characterized by a second-order acylation rate ...
First-line antibiotics for uncomplicated UTI remain more effective than fluoroquinolones and beta-lactams in a retrospective ...
The intravenous antibiotic Emblaveo, a combination of aztreonam and avibactam approved in Europe last year, was developed in ...
“ß-lactams are . . . the go-to antibiotics and being able to get that sensitivity back is absolutely critical.” ß-lactam antibiotics, which include penicillins such as methicillin, kill bacteria by ...
It is a first-generation cephalosporin antibiotic, meaning that it was among the first cephalosporins developed. It is also ...
"Various types of ß-lactam antibiotics such as penicillin, which kill bacteria by targeting the synthesis of the cell wall, are among the most common treatments today. However, as resistance is ...
Wockhardt's Zaynich, an investigational antibiotic, has been under evaluation for its efficacy in treating complicated ...