Nature20d
Poretti-Boltshauser Syndrome And Laminin Biology
Another significant area of research has been the role of specific laminin isoforms, such as Laminin N-terminus α31 (LaNt α31), in cancer biology. Studies have shown that LaNt α31 is ...
Nature22d
Properly formed but improperly localized synaptic specializations in the absence of laminin α4
Few active zones or junctional folds form in mice lacking the laminin β2 chain, which is normally concentrated in the synaptic cleft. β2 and the broadly expressed γ1 chain form heterotrimers ...
eLife3d
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...