Furosemide injection was previously approved to treat congestion from fluid buildup in adults with chronic heart failure.

Future Cardiol. 2012;8(5):707-728. These data come from reports of ototoxicity of 6.4% with furosemide compared with 1 and <1% for bumetanide and torsemide, respectively. [38] Acute kidney failure ...

[38] In the setting of refractory edema (inadequate diuretic response after 120 mg oral furosemide), 10 CHF patients were administered furosemide infusions titrated to clinically adequate diuresis.