Leptin, produced primarily by fat cells, typically signals the brain when enough food has been consumed, helping to regulate energy and appetite. But in some individuals with obesity, this ...
Hormones play a crucial role in regulating weight gain and metabolism, influencing how the body stores fat, burns energy, and manages hunger. Several key hormones interact in complex ways to ...
In humans, many leptin deficiency syndromes are responsive to leptin replacement therapy. As leptin is involved in numerous pathways, the effects of too little leptin are widespread (including ...
BM stem cells reside in niches ... as well as specific transgenic strains like leptin receptor-cre recombinase (Lepr-cre), nerve/glial antigen 2-cre estrogen receptor (Ng2-creERTM), and ...