INTRODUCTION: We have shown previously that treatment with pegylated leptin peptide receptor antagonist 2 (PEG-LPrA2) reduced the expression of vascular endothelial growth factor (VEGF), vascular ...

Completely overhauling your diet and exercise habits can certainly do the trick when it comes to weight loss, but making ...

Leptin, encoded by the obese gene, is a peptide hormone that is produced by peripheral adipocytes. Its concentration in the circulation is proportional to fat stores and it serves as an ...

GLP-1 was obtained from Bachem (Torrance, CA), Ex4 was obtained from California Peptide Research (Napa, CA), and both were dissolved in sterile 0.9% saline. Recombinant mouse leptin (Dr.

Peptides are small molecules composed of two ... while also normalizing the hunger and fullness hormones ghrelin and leptin. Peptides work in the body because they act as signaling molecules ...

Substance P is a small peptide of the tachykinin family that ... Two mouse models, one of diet-induced and one of leptin-deficient obesity, were used to test the effects of NK1R antagonism on ...

More than 100 projects have received support as part of the 2024 European Research Council (ERC) proof of concept competition ...