In humans, many leptin deficiency syndromes are responsive to leptin replacement therapy. As leptin is involved in numerous pathways, the effects of too little leptin are widespread (including ...

View Full Profile. Learn about our Editorial Policies. “Up until now, the scientific community thought that leptin acts exclusively in neurons to modulate behavior and body weight,” Horvath said in a ...

Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin resistance. In lean individuals, fat cells produce the hormone leptin ...

The NEJM editorial mentioned in the story appeared in the Aug. 29, 1996, issue, Vol. 335, No. 9. Yinglin Bai, Shaoying Zhang, Kyung-Sup Kim, Jung-Kee Lee, and Ki-Han Kim, Department of Biochemistry, ...

In "Leptin Receptor Neurons in the dorsomedial hypothalamus require distinct neuronal subsets for thermogenesis and weight loss," researchers laid out the pathways, chemicals, neurons and brain ...

Though a complex interplay of genes, diet, and environment contribute, 90% of cases share one thing in common: leptin ...

Though a complex interplay of genes, diet, and environment contribute, 90% of cases have leptin resistance in common. In lean individuals, fat cells produce the hormone leptin, which suppresses ...