Work at Artivila (Shenzhen) Innovation Center Ltd. has led to the discovery of new leucine-rich repeat kinase 2 (LRRK2; Dardarin) inhibitors reported to be useful for the treatment of cancer, leprosy, ...

In doing so, she found that cancer cells have higher levels of a leucine-shuttling tRNA compared to normal cells. The tRNA in question recognizes the codon GAU on an mRNA molecule. But even more ...

A first-in-human trial of Arvinas’ investigational Parkinson’s’ disease therapy, ARV-102, has been able to demonstrate a drop in the multifunctional protein that has been associated with the disease ...