This effect was also observed in a special mouse model for lupus, in which mice had been genetically engineered to develop a lupus-like disease. Gluconolactone improved the function of Tregs in the ...

To verify that this mutation causes lupus, the team used CRISPR gene-editing technology to introduce the mutation into mice.

Project title: Investigation of the differentiation of male and female derived stem cells to pro-inflammatory and anti-inflammatory cells in a chimeric lupus mouse model Mentor: Trine N. Jorgensen ...

B6/lpr mice, which develop lupus-like autoimmunity and nephritis, have an expanded population of double-negative (DN) T cells that produce IL-17. Mice of this strain deficient for interleukin (IL ...

This effect was also observed in a special mouse model for lupus, in which mice had been genetically engineered to develop a lupus-like disease. Gluconolactone improved the function of Tregs in the ...

This effect was also observed in a special mouse model for lupus, in which mice had been genetically engineered to develop a lupus-like disease. Gluconolactone improved the function of Tregs in ...

Following treatment with pristane, a chemical that induces lupus, male mice with Xist had higher levels of autoantibodies than male mice without Xist expression, and their levels were closer to those ...

Although the unpurified extract is reportedly an effective treatment for lupus nephritis in mice, the effects of triptolide and tripdiolide, thought to be the two most therapeutically active ...