Does MYC binding to chromatin serve transcription-independent functions, including the regulation of chromosomal integrity, gene expression, chromatin structure, cellular replication and genomic ...

Expression of the cell cycle inhibitor p15 INK4b is suppressed by the Myc oncoprotein and induced by transforming growth factor-β (TGF-β). The transcription factor Miz-1 activates the Ink4b ...

However, the study published Aug. 28 in Nature Communications identifies the MYC gene as a common denominator across prostate cancers. The work demonstrates that initial MYC activation attracts ...

These lncRNAs, located near the MYC oncogene, exhibited significantly ... “We found a direct link between eating fiber and modulation of gene function that has anti-cancer effects,” said ...