The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside ...

1 There are three different macrophage types, naïve (M0), antitumor (M1), and protumor (M2). M1 macrophages accumulate at the tumor and exert antitumor activity. Researchers have attempted to use them ...

These likely represent blood precursors of pathogenic tissue macrophages. This work is important, because it not only defines a new monocyte cell taxonomy relevant for RA—with 11 continuous cell ...

Over the past ten years, we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse ...