One significant finding in recent studies is the dual role of complement components in cancer progression. For instance, C1q+ tumor-associated macrophages (TAM) have been identified as markers of ...
IgG activates complement, and binds Fc-receptors (FcRs) on macrophages and neutrophils, upon which pathogens coated with IgG are phagocytosed by these cells. 14 Intriguingly, obesity is associated ...