Lysosome-related organelles (LROs ... As the LPS signal is mediated through TLR4 on DCs and macrophages, and these cells do not typically express granzymes, it will be interesting to unravel ...

When functional, a lysosome can break down large sugars into small sugars, which are then used as an energy source. In LSDs, these macrophage lysosomes become swollen and filled with waste.