To grow, cancer tumors must hijack the immune system for their needs. One of the main tricks that most tumors use is to ...

The cell and drug components give MDCs a dual mechanism-of-action that combines direct cancer-cell killing and immune activation. Macrophages are ideal for getting ferritin cages to cancer cells.

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Thanks to the NIH, researchers like Andrew Ewald have advanced our understanding of what allows a cancer cell from one part ...

These likely represent blood precursors of pathogenic tissue macrophages. This work is important, because it not only defines a new monocyte cell taxonomy relevant for RA—with 11 continuous cell ...

Researchers in South Korea have proposed a novel cancer immunotherapy approach that could complement existing CAR-T (Chimeric ...

In this project, based on our study using mouse and human ES cells, we will establish methods to induce differentiation of human iPS cells into dendritic cells and macrophages. Our project also ...

Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian cancer.