Recently developed major histocompatibility complex (MHC) multimer technologies allow visualization and isolation of antigen-specific T cells. However, functional analysis and in vivo transfer of ...

研究背景 主要组织相容性复合体（Major Histocompatibility Complex, MHC）是一类在免疫系统中发挥关键作用的蛋白质分子。抗原被降解后以多肽形式 ...

T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...

"One of the major issues in molecular immunology is determining how a limited number of major histocompatibility complex (MHC) molecules in any individual can recognize and present a seemingly ...

Some of these antigenic peptide fragments, which are between eight and 12 residues in length, are presented on the cell surface by class I major histocompatibility complex (MHC I) proteins.