The molecular mechanisms of action, clinical development, and efficacy and safety of targeted antineoplastic drugs are discussed. Recently introduced mechanism-based systemic therapies for cancer ...

Rheumatoid arthritis (RA) is an autoimmune disorder affecting millions worldwide, causing chronic inflammation, debilitating ...

A research team, affiliated with UNIST has unveiled soft self-standing protein hydrogels that selectively deliver drugs, ...

The company’s ultimate goal is to develop a suite of solutions that allow short-RNA medicines to be delivered in a highly targeted ... via an ecosystem of delivery mechanisms.

DNA nanorobots control artificial cell membranes, mimicking living cell functions It creates transport channels in synthetic cells to enhance drug delivery ... This mechanism was developed using ...

On the other hand, mechanisms of acquired resistance to 'pathway-targeted' drugs, such as the various clinically active kinase inhibitors, have been somewhat more straightforward to elucidate and ...

Horizon’s aim is to help its partners to identify, evaluate and validate targets, to understand drug mechanisms of action, and to facilitate studies involving patient stratification. Horizon has ...

These solutions include molecular conjugates and nanoparticles for targeted drug delivery, new imaging modalities for surgical guidance and detection ... epigenetics-based methods to determine ...

The breakthrough in drug delivery hinges on the development of nanoarchaeosomes, which are nanoparticles loaded with ...

By harnessing various propulsion mechanisms, nanoswimmers offer exciting opportunities for targeted drug delivery, biosensing, environmental remediation, and studying fundamental aspects of motion at ...

Biomedical microrobots could revolutionize future cancer treatments, reliably delivering targeted doses of toxic cancer-fighting drugs to destroy ... therapeutic agents integrated into the hydrogel ...

More information: Bassel Alsaed et al, Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment, Nature Communications (2025 ...