Cholesterol enhances the binding of FGF2 to PI(4,5)P2-containing membranes, facilitating its oligomerization and subsequent secretion[3][4]. This lipid-mediated mechanism underscores the ...

However, the underlying mechanisms of this restored glucagon secretion and whether the same mechanism is effective in humans ...

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life- ...

GLP-1's release is stimulated by certain foods and gut microbes, and its mechanism of action is mimicked by drugs ... vulgatus, it boosted GLP-1 secretion, which then also triggered the secretion of ...

It is secreted by enteroendocrine cells in response to nutrient intake, and its secretion is influenced by various mechanisms involving different nutrients. Recent research has focused on ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed by a team led by Osaka Metropolitan University ...

Crohn's disease and ulcerative colitis are idiopathic, chronic, relapsing, inflammatory conditions that are immunologically mediated. Although their exact etiologies remain uncertain, results from ...

These findings may offer more personalized treatment and prevention recommendations for patients with psoriasis.

Because either those, or drugs that unjam endosomes, will break the vicious cycle, a cycle that leads to Aβ secretion and neurodegeneration through intraneuronal mechanisms. Genetics support this ...

Aging cells secrete substances known to promote the growth of cancer cells. The development of drugs that can selectively kill these cells or inhibit the secretion of substances is ongoing.

Zhen Huang, and Åke Sjöholm. "Ethanol acutely stimulates islet blood flow, amplifies insulin secretion, and induces hypoglycemia via NO and vagally mediated mechanisms" ...

A new study led by Dr. Saifur Khan, Ph.D., cardiology research faculty member at the University of Pittsburgh Vascular Medicine Institute, is the first to identify molecular mechanisms of the ...