Studies of murine models suggest that aberrant granule-cell development might result in a subset of medulloblastoma tumors; recently identified cerebellar neural stem cells might be another ...

Medulloblastoma are the most common type of ... One gene that HLX increases expression of is MYC, which also increases the expression of several other cancer-causing genes, causing a cascade ...

The lead researchers have acknowledged the findings as potentially transformative for the treatment of the most common childhood brain cancer, medulloblastoma, and could apply to other brain ...

SickKids researchers identified the KCNB2 gene as a key driver of medulloblastoma tumor growth. Blocking KCNB2 disrupts potassium channels, causing tumor-propagating cells to swell and lose integrity.