For the first time in 30 years, a new drug class known as the CGRP-Antagonists (calcitonin gene-related peptide) has emerged.

Importantly, no serious adverse events were associated with TMS. The fact that migraine pathophysiology is highly likely to have both neuronal and vascular components, which probably interact in a ...

Delivering room-temperature air through the nose to cool the sphenopalatine ganglion taps into a powerful neuromodulatory ...

"Using dry room-temperature air, Mi-Helper elicits local cooling of the nasal cavity, which calms or inhibits the SPG, ...

Migraine has a very complex pathophysiology in which hormonal status, a possible genetic basis, and contributing factors such as PFO in specific subset of patients, all increase the difficulty in ...

Researchers used liquid chromatography–mass spectrometry (LC–MS) in their proteomic analysis to compare the serum proteome of migraine patients with healthy controls and to identify differentially ...

Migraine is one of the most severe and debilitating brain disorders. Most scientists accept that it involves activation and sensitization of the trigeminovascular system, which includes the ...

A landmark migraine study presented at AAN 2025 identified 778 new genetic variants linked to migraine across ancestries in ...

These three branches are also involved in migraine pathophysiology — more on that in a bit. Symptoms can come and go, ...