3D reconstruction of a microscope image: red is the membrane and green is clumped prion protein. In order to gain ... to explore the role of a membrane anchor on the folding and aggregation ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

D. Hockenbery, G. Nunez, Curt Milliman, R.D. Schreiber, S.J. Korsmeyer, "Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death," Nature ...

Lipid anchors on nerve cell membranes stabilize prion protein folding, inhibiting aggregation. Membrane-anchored proteins clump only when exposed to pre-formed protein aggregates, simulating ...

The researchers conducted their experiments in samples of yeast with mutations, or alterations, in a mitochondrial membrane protein called AAC and samples of human cells that modeled a person with ...

Mitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ (Ca2+mito) plays a dual role in physiological processes ...

2 The team fused DAAO to either a nucleosome protein or a mitochondrial membrane protein to study the effects of hydrogen peroxide produced at these specific locations. The team hypothesized that ...