A large structure called the mitotic spindle also forms from long proteins called microtubules on each side, or pole, of the cell. During prometaphase, the nuclear envelope that encloses the ...

Cell division is essential to the propagation of life. During cell division, mitotic spindles segregate duplicated chromosomes with high fidelity. Spindle structure depends on the proper polar ...

The subsequent breakdown of the nuclear envelope terminates prophase and initiates prometaphase, during which the chromosomes become attached to and positioned on the mitotic spindle as it forms.

Mitotic spindles are dynamic, self-organizing, intracellular structures that are essential for cell division. Spindles are composed of proteins, cytoskeletal elements and microtubules, which are a key ...