HSF1 transiently accumulates in the nucleus of human monocytes undergoing macrophage differentiation, including M-CSF-treated peripheral blood monocytes and phorbol ester-treated THP1 cells.

Consistent with lung surfactant build up in the children’s lungs and the monocyte migration impairment, the researchers found a decreased number of alveolar macrophages in their patients’ ...

Over the course of a week, the monocytes transform into cells that are very much like alveolar macrophages that can then be ...