The research team found that a specific muscle protein, known as MEF2C, is significantly reduced in muscle cells with CP.

Or, Ng realized, they could simply do both. To increase their chances of success, and in hopes of learning more about fiber subtypes, Ng and his team started with mouse leg muscle tissue, as its ...

Skeletal muscle organoids help scientists bypass bottlenecks in satellite cell production for muscle regeneration research.

Additionally, we demonstrated that miR-486 overexpression in dystrophic mouse muscles can block the progression of DMD symptoms and improve overall muscle performance and physiology (Alexander et al., ...

Next, using a genetically manipulated mouse model, which boosted NAD+ production specifically in muscle stem cells, the team ...

We previously found that local delivery of mIgf-1 to individual mouse muscles by AAV virus-mediated gene transfer blocks age-related loss of muscle size and strength 26, which is at least ...

Stem cell biology; regeneration; skeletal muscle regeneration and aging; skeletal muscle stem cells and gene therapy; growth factors and signal transduction; mouse molecular genetics; muscular ...