Much like the insulation around the wires in electrical systems, glial cells form a membraneous sheath surrounding axons called myelin ... axons and even the entire neuron vulnerable to degeneration.

The paper K.M. Young et al., “Oligodendrocyte dynamics in the healthy adult CNS: evidence for myelin remodeling,” Neuron, 77:873-85, 2013. The problem Oligodendrocytes (OLs) produce the myelin sheaths ...

When the neuron is triggered, it activates voltage-gated sodium channels at the beginning of the axon. This causes an influx of positive sodium ions into the cell, raising the voltage and depolarizing ...

Multiple sclerosis, a neuroinflammatory disease that affects nearly 3 million people worldwide, causes a loss of myelin ...

The research report titled: “Selective retinoid X receptor agonism promotes functional recovery and myelin repair in experimental ... EAE is a commonly used model of neuroinflammation in human ...