Objective: To investigate the efficacy and tolerability of high-dose N-acetylcysteine (NAC) in the treatment of patients with exacerbations of chronic obstructive pulmonary disease (COPD).

N-Acetylcysteine (NAC) is a powerful antioxidant and immune-supporting compound with broad health benefits. From clearing lung congestion and reducing inflammation to enhancing brain function and ...

Patients' disease characteristics and demographic data at screening (T0) are reported in Table 1. At the screening visit (T0), CRP levels were higher than normal (=0.5 mg/dL) in 81 (66.4% ...