The researchers next showed that when macrophages were exposed to inflammatory signals, their activity changed alongside shifts in how a key immune regulator, known as nuclear factor kappa-B (NF-κB), ...

The nuclear factor (NF)-κB, inhibitor of NF-κB (IκB) and IκB kinase (IKK) pathway is activated in response to various stimuli in many cell types. NF-κB is activated by many mechanisms ...