而NKT细胞扩增就复杂的多，本身NKT细胞占外周血T细胞不到1%，比例极低，需要CD1d+APC和α-GalCer刺激才能扩增。扩增效率远低于NK细胞，一般来说都不到10倍。

本研究揭示了HSV-1 UL56基因通过降解CD1d蛋白抑制NKT细胞功能的分子机制，为抗HSV-1感染研究提供了新靶点。 研究背景 单纯疱疹病毒（HSV-1）是一种具有强大免疫逃逸能力的病原体，其感染可引起多种疾病。CD1d限制性自然杀伤T（NKT）细胞在抗HSV-1免疫中发挥重要 ...

The causes of MDS remain poorly defined, but several studies have reported the NKT cell compartment of patients with MDS is deficient in number and functionally defective. In support of a central ...

A new study published in Mucosal Immunology shows that α-galactosylceramide (α-GalCer) serves as a potent adjuvant by activating natural killer T (NKT) cells, which promote effective cross ...

GRI Bio's focus on an innovative pipeline targeting Natural Killer T (NKT) cell modulators indicates a strategic approach to treating inflammatory and fibrotic diseases, suggesting long-term ...

The Virtual Investor CEO Connect featuring GRI Bio is now available here. Additional videos from the “What This Means” series are available on demand at https://virtualinvestorco.com/gri/. About GRI ...

Moffitt Cancer Center researchers have discovered a promising new vaccine strategy for treating a specific type of breast ...

More information: Tomoyoshi Tamura et al, Diverse NKT cells regulate early inflammation and neurological outcomes after cardiac arrest and resuscitation, Science Translational Medicine (2024). DOI ...

LA JOLLA, CA, March 11, 2025 (GLOBE NEWSWIRE) -- GRI Bio, Inc. (NASDAQ: GRI) (“GRI Bio” or the “Company”), a biotechnology company advancing an innovative pipeline of Natural Killer T (“NKT”) cell ...

LA JOLLA, CA, Feb. 19, 2025 (GLOBE NEWSWIRE) -- GRI Bio, Inc. (NASDAQ: GRI) (“GRI Bio” or the “Company”), a biotechnology company advancing an innovative pipeline of Natural Killer T (“NKT”) cell ...