在技术方法上，研究人员运用了多种 RNA 测序技术，如 Nanopore 长读长直接 RNA 测序、无扩增直接 cDNA 测序、PCR 扩增 cDNA 测序、PacBio IsoSeq 以及短读长 cDNA 测序。同时，他们还引入了多种已知浓度的内参 RNA（spike-in RNAs），并进行了转录组范围的 N 6 - 甲基腺苷（m 6 A ...

Building on these discoveries, researchers have developed a nanopore-based tool that could revolutionize diagnostics. Current diagnostic methods often require large quantities of biological ...

Oxford Nanopore Technologies today announced the expansion of its Compatible Products Programme (CPP), welcoming a new cohort of leading partners whose products now integrate seamlessly with Oxford ...

Nano-tRNAseq is based on nanopore sequencing ... with a corresponding change in the electrical current that occurs as each nucleotide passes through the pore. Computer programs detect changes ...

The Oxford Nanopore MinION represents a portable, real-time sequencing device that produces ultra-long reads from individual DNA and RNA molecules without the need for PCR amplification. Each MinION ...

For example, will we need an improved motor protein for certain types of protein sequences? Will a different pore size make our method more sensitive because our current nanopore was optimized for DNA ...

Nanopore sequencing addresses these limitations to advance metagenomics research. Download this white paper from Oxford Nanopore Technologies to learn the advantages of employing nanopore sequencing ...

Oxford Nanopore Technologies PLC makes a novel generation of DNA/RNA sequencing technology that provides rich data, is fast, accessible, and easy to use. It is the only sequencing technology that ...