We will also review a number of published findings regarding the role of the cytokine macrophage migration inhibitory ... The time course and selective nature of the MIF-induced response were ...

now report that the deletion of two transcription factors linked to monocyte differentiation could confer limitless self-renewal capacity to mature differentiated macrophages. Surprisingly ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.