The 3D brain map includes more than 200,000 cells, 523 million synapses and over two miles of axons, representing the most detailed wiring diagram of a piece of mammal brain ever constructed ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 ...

Older adults with ADHD are at higher risk of age-related dementias like Alzheimer's disease, and an international team of ...

Revealing the fundamental principles of how neural circuits are organized and ... even when they belong to the same axon and contact the same postsynaptic target. What is the basis for this ...

In parallel, the NfL is an indicator of neuronal damage in the brain, more specifically of neuronal axons, which are essential for nerve transmission. High blood levels of NfL reflect axon damage in ...

Neurodegenerative conditions such as Parkinson's disease and Alzheimer's involve progressive neuronal loss due to ...

Supported by funds from NINDS, the Watkins Lab is uncovering how two prominent stress pathways are coordinately initiated by axon injury and the mechanisms by which these two arms of the response ...

Since receptors for axon guidance on the cell surface have ... neurotrophin-3, neurotrophin 4/5 Neuronal survival, proliferation of oligodendrocyte progenitors, down-regulate macrophage's ...