The results of the phase 1 study are expected towards the end of 2022. MBS8 triggers the migration of neutrophils into tumor tissue and killing of cancer cells within 24 hours. “Neutrophils are ...

This dual functionality suggests that neutrophils are highly plastic, with their actions shaped by dynamic environmental cues within the tumor microenvironment (TME). Understanding this complexity ...

An immuno-oncology targeting panel accurately characterized tumor-resident immune cells and located pathologically and clinically relevant tumor microenvironment features. Cancer development and ...

Dr. Won Jin Ho presented a talk as part of the Immunology Neighborhood Seminar on “Overcoming the tumor immune ...

16 in Nature Biotechnology, point to a potential new treatment that may benefit more patients than current therapeutic options. “Traditional therapies target one molecule in the tumor microenvironment ...

Prior studies in both animals and humans have reported that neutrophils can cross the blood-brain barrier, and although these cells are not typically attracted to glioblastomas, they are recruited at ...

Triple-negative breast cancer (TNBC) is one of the most aggressive and difficult-to-treat forms of breast cancer, lacking targeted therapies due to its molecular characteristics. Tumor-associated ...

Other oncology research teams are investigating the roles of extrachromosomal DNA, DNA damage responses and white blood cells called neutrophils in cancer.