Gene mutations occur when one nucleotide in a codon is switched. In non-synonymous mutations, this disrupts the codon's function to code for its amino acid. In synonymous mutations, the codon ...

When the team tested the algorithms’ predictive ability on a new subset of the data, Tuller was surprised to find that these algorithms performed just as well as algorithms that had been trained on ...

Synonymous mutations have long been ignored in cancer studies since they don’t affect the amino acid sequences of proteins. But research increasingly reveals that they can have disease-driving effects ...

Tumor mutational load (TML) is a measure of the total number of non-synonymous mutations per coding area A non-synonymous mutation is a change in the DNA sequence that results in the alteration of ...