Around 5-10% of women with breast cancer carry a germline altered gene, including BRCA1 and BRCA2. In the Scottish Northern Isles of Orkney and ... addressing an unmet need for targeted therapies for ...

We applied the principle of synthetic lethality to discover a novel strategy for cancer treatment for patients with BRCA1 or BRCA2 gene mutations. We demonstrated that drugs called PARP inhibitors ...

Doctors say hereditary breast and ovarian cancers stand as significant concerns due to their widespread occurrence and ...

In August, her fears were realised with a diagnosis of Triple Negative Breast Cancer and the revelation of a mutated BRCA1 gene. Steph recalls the profound moment of learning her condition ...

Certain inherited gene mutations, like those in the BRCA1 and BRCA2 genes, can dramatically increase the likelihood of developing cancers such as breast and ovarian cancer. Conditions like Lynch ...

At least 260 women born with mutated ... by genetic factors and the removal of breasts, ovaries or uterine tubes can save lives. The organization said women with mutations of their BRCA1 and ...

One of the drugs now available is olaparib - also known under the brand name Lynparza- for adults with breast cancer linked to the BRCA1 gene, or those with mutated HER2-negative advanced breast ...