For the first time, scientists at the Francis Crick Institute have successfully developed human stem cell models that include a functional notochord—a crucial tissue in embryonic development ...

Masatake Kai and Professor Makoto Kondo focused on this paraxial protocadherin (PAPC), which is excluded when dividing cells migrate and form the notochord in the embryo. The findings were ...

"What's particularly exciting is that the notochord in our lab-grown structures appears to function similarly to how it would in a developing embryo ... seen this in non-human primates," David ...