2020). Activation of Nrf2 can mitigate irreversible cardiomyocyte damage by regulating intracellular redox signaling pathways (Huang et al., 2022; Bubb et al., 2017). We and others demonstrated that ...

suggesting that PUE does reduce oxidative stress by activating the PI3K/Akt/Nrf2 signaling pathway. Finally, by administering Nrf2 inhibitor and HO-1 inhibitor, we found that the decrease in Nrf2 ...

Continuing in its mission to elucidate the role of metal nutrients in human biology, the Chang Lab also offers a possible ...

The aim of this study was to elucidate the role of nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that maintains the cellular defence against oxidative stress, in RA.